Oligonucleotide Synthesis Market

Global Oligonucleotide Synthesis Market Research By Product (Synthesized Oligonucleotides, Reagents, and Equipment), By Type (Custom Oligos and Predesigned Oligos), and By End-User (Hospitals, Pharmaceutical & Biotechnology Companies, Academic Research Institutes and Other) Forecast 2021-2027

Published: Apr 2020 | Report Code: OMR2025511 | Category : Biotechnology | Delivery Format: /

The global oligonucleotide synthesis market is growing at a considerable CAGR of 11.0% during the forecast period. Increasing research activity, rising synthesis technological advancements are two of the prime factors affecting and driving the market. Additionally, the increasing focus associated with personalized medicines along with growing investment in the healthcare sector is also estimated to be the key factor that is contributing significantly towards the growth of the market. However, lack of skilled professionals and high cost of investment is the major factor constraints that are hindering the growth of the global oligonucleotide synthesis market across the globe. 

Moreover, increasing benefits from the ongoing development of genomics and rising R&D expenditure are some of the key factors that are creating opportunities in the market. New product launches in the market are likely to drive the growth of the global oligonucleotide synthesis market. For instance, in February 2021, Sarepta Therapeutics had received the approval and clearance for its AMONDYS 45 (casimersen) from the U.S. Food and Drug Administration (FDA). The AMONDYS 45 is considered to be an antisense oligonucleotide for the purpose of giving effective treatment of Duchenne muscular dystrophy (DMD) in patients confirmed from mutation amenable to exon 45 skipping.

Impact of COVID-19 Pandemic on the Global Oligonucleotide Synthesis Market

The global oligonucleotide synthesis market is hardly hit by the COVID-19 pandemic since December 2019. The COVID-19 pandemic had brought a lot of disruption across the globe. However, the various pharmaceutical & biotechnology companies have come forward in order to provide research efforts by providing oligo products. 

Segmental Outlook 

The global oligonucleotide synthesis market is segmented based on product, type, and end-user. Based on product, the market is segmented into synthesized oligonucleotides, reagents, and equipment. By type, the market is segmented into custom oligos and predesigned oligos. Further, based on end-user the market is segmented into hospitals, pharmaceutical & biotechnology companies, academic research institutes, and other. 

Global Oligonucleotide Synthesis Market Share by Product 2020 (%)

Global Oligonucleotide Synthesis Market Share by Product

Based on the product, the synthesized oligonucleotides hold a significant share in the market. The growing number of FDA-approved drugs along with the increasing adoption of PCR technologies across research and diagnostic fields are some of the key factors that are driving the growth of the segment in the market.

Regional Outlooks

The global oligonucleotide synthesis market is analyzed based on the geographical regions that are contributing significantly towards the growth of the market. Based on the geography, the market is segmented into North America, Europe, Asia-Pacific, and the Rest of the World. North America held a considerable share in 2020 in the global oligonucleotide synthesis market. In North America, rising personalized therapeutics development is one of the prime factors affecting the growth of the market in the region. Additionally, the increasing demand related to high-quality research tools along with the existence of a large number of players is some other main factors that are providing support to the growth of the market in the region.

Global Oligonucleotide Synthesis Market, by Region 2021-2027

Global Oligonucleotide Synthesis Market, by Region

Asia-Pacific will have Considerable Growth in the Global Oligonucleotide Synthesis Market

Asia-Pacific region is expected to witness significant growth opportunities for the market. Increasing initiatives by government across the region is likely to drive the growth of the regional market. Additionally, key market companies expanding their reach along with rising health care expenditure in this region, especially in South Korea, China, and India are impacting the growth of the market. Additionally, an increase in R&D funding is another factor that is also affecting the growth of the market.

Market Player Outlook

Key players of the global oligonucleotide synthesis market are Danaher Corp., Thermo Fisher Scientific Inc., Merck KgaA, Maravai LifeSciences, and GenScript. To survive in the market, these players adopt different marketing strategies such as product launches and mergers and acquisitions. For instance, in June 2021, Danaher Corp. had set forth to enter into an agreement in order to do the acquisition of Aldevron for around $9.6 billion. Through this acquisition, the company will enlarge its capabilities into the prime field of genomic medicine along with supporting its customers for the purpose of bringing life-saving therapies and vaccines at a faster speed to the market.

In March 2021, Nitto Denko Avecia Inc. had done an investment of around $27 billion for the enlargement of oligonucleotide therapeutics manufacturing capacity in its business for common diseases and intractable diseases such as cancer.

In February 2021, one of the providers in bioanalytical testing named Eton Bioscience, Inc. had done acquisition of Beacon Discovery that is considered to be a preeminent drug discovery and contract research organization (CRO) that emphasis on G-Protein Coupled Receptor (GPCR) research. Through this acquisition, the company will enhance its capabilities along with innovative methods for supporting and boosting drug discovery research and development.

In December 2019, Sarepta Therapeutics had received the approval and clearance for its VYONDYS 53 (golodirsen) from the U.S. Food and Drug Administration (FDA). The VYONDYS 53 is considered to be an antisense oligonucleotide for the purpose of giving effective treatment of Duchenne muscular dystrophy (DMD) in patients.

The Report Covers

  • Market value data analysis of 2020 and forecast to 2027.
  • Annualized market revenues ($ million) for each market segment.
  • Country-wise analysis of major geographical regions.
  • Key companies operating in the global oligonucleotide synthesis market based on the availability of data, information related to new product launches, and relevant news is also available in the report.
  • Analysis of business strategies by identifying the key market segments positioned for strong growth in the future.
  • Analysis of market-entry and market expansion strategies.
  • Competitive strategies by identifying ‘who-stands-where in the market.

1. Report Summary

Current Industry Analysis and Growth Potential Outlook

Impact of COVID-19 on the Global Oligonucleotide SynthesisIndustry 

Recovery Scenario of Global Oligonucleotide SynthesisIndustry

1.1. Research Methods and Tools

1.2. Market Breakdown

1.2.1. By Segments

1.2.2. By Geography

2. Market Overview and Insights

2.1. Scope of the Report

2.2. Analyst Insight & Current Market Trends

2.2.1. Key Findings

2.2.2. Recommendations

2.2.3. Conclusion

3. Competitive Landscape

3.1. Key Company Analysis

3.1.1. Overview  

3.1.2. Financial Analysis 

3.1.3. SWOT Analysis

3.1.4. Recent Developments  

3.2. Key Strategy Analysis

3.3. Impact of Covid-19 on Key Players

4. Market Determinants

4.1. Motivators

4.2. Restraints

4.3. Opportunities

5. Market Segmentation

5.1. Global Oligonucleotide Synthesis Market by Product

5.1.1. Synthesized Oligonucleotides

5.1.2. Reagents

5.1.3. Equipment

5.2. Global Oligonucleotide Synthesis Market by Type

5.2.1. Custom Oligos

5.2.2. Predesigned Oligos

5.3. Global Oligonucleotide Synthesis Market by End-User

5.3.1. Hospitals

5.3.2. Pharmaceutical & Biotechnology Companies

5.3.3. Academic Research Institutes

5.3.4. Other (Diagnostic Laboratories)

6. Regional Analysis

6.1. North America

6.1.1. United States

6.1.2. Canada

6.2. Europe

6.2.1. UK

6.2.2. Germany

6.2.3. Italy

6.2.4. Spain

6.2.5. France

6.2.6. Rest of Europe 

6.3. Asia-Pacific

6.3.1. China

6.3.2. India

6.3.3. Japan

6.3.4. South Korea

6.3.5. Rest of Asia-Pacific 

6.4. Rest of the World

7. Company Profiles 

7.1. ATDBio Ltd.

7.2. BioAutomation

7.3. Biogen Inc.

7.4. Biolegio B.V.

7.5. BIONEER CORP.

7.6. Danaher Corp.

7.7. Eurofins Scientific

7.8. Eton Bioscience, Inc.

7.9. GenScript

7.10. LGC Biosearch Technologies

7.11. Maravai LifeSciences

7.12. Merck KgaA

7.13. Nitto Denko Avecia Inc.

7.14. PolyGen GmbH

7.15. Quintara Biosciences

7.16. Sarepta Therapeutics

7.17. Thermo Fisher Scientific Inc.


1. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS, 2020-2027 ($ MILLION)

2. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET BY PRODUCT, 2020-2027 ($ MILLION)

3. GLOBAL SYNTHESIZED OLIGONUCLEOTIDES MARKET BY REGION, 2020-2027 ($ MILLION)

4. GLOBAL REAGENTS MARKET BY REGION, 2020-2027 ($ MILLION)

5. GLOBAL EQUIPMENT MARKET BY REGION, 2020-2027 ($ MILLION)

6. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET BY TYPE, 2020-2027 ($ MILLION)

7. GLOBAL CUSTOM OLIGOS MARKET BY REGION, 2020-2027 ($ MILLION)

8. GLOBAL PREDESIGNED OLIGOS MARKET BY REGION, 2020-2027 ($ MILLION)

9. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET BY END-USER, 2020-2027 ($ MILLION)

10. GLOBAL HOSPITALS MARKET BY REGION, 2020-2027 ($ MILLION)

11. GLOBAL PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES MARKET BY REGION, 2020-2027 ($ MILLION)

12. GLOBAL ACADEMIC RESEARCH INSTITUTES MARKET BY REGION, 2020-2027 ($ MILLION)

13. GLOBAL OTHER OLIGONUCLEOTIDE SYNTHESIS MARKET BY REGION, 2020-2027 ($ MILLION)

14. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY GEOGRAPHY, 2020-2027 ($ MILLION)

15. NORTH AMERICAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2020-2027 ($ MILLION)

16. NORTH AMERICAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2020-2027 ($ MILLION)

17. NORTH AMERICAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BYTYPE, 2020-2027 ($ MILLION)

18. NORTH AMERICAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2020-2027 ($ MILLION)

19. EUROPEAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2020-2027 ($ MILLION)

20. EUROPEAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2020-2027 ($ MILLION)

21. EUROPEAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY TYPE, 2020-2027 ($ MILLION)

22. EUROPEAN OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2020-2027 ($ MILLION)

23. ASIA-PACIFIC OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2020-2027 ($ MILLION)

24. ASIA-PACIFIC OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2020-2027 ($ MILLION)

25. ASIA-PACIFIC OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY TYPE, 2020-2027 ($ MILLION)

26. ASIA-PACIFIC OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2020-2027 ($ MILLION)

27. REST OF THE WORLD OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2020-2027 ($ MILLION)

28. REST OF THE WORLD OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY TYPE, 2020-2027 ($ MILLION)

29. REST OF THE WORLD OLIGONUCLEOTIDE SYNTHESIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2020-2027 ($ MILLION)


1. IMPACT OF COVID-19 ON GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET, 2020-2027 ($ MILLION)

2. IMPACT OF COVID-19 ON GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET SHARE BY SEGMENT, 2020-2027 ($ MILLION)

3. RECOVERY OF GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET, 2021-2027 (%)

4. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET SHARE BY PRODUCT, 2020 VS 2027 (%)

5. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET SHARE BY TYPE, 2020 VS 2027 (%)

6. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET SHARE BY END-USER, 2020 VS 2027 (%)

7. GLOBAL OLIGONUCLEOTIDE SYNTHESIS MARKET SHARE BY GEOGRAPHY, 2020 VS 2027 (%)

8. GLOBAL SYNTHESIZED OLIGONUCLEOTIDES MARKET BY REGION, 2020 VS 2027 (%)

9. GLOBAL REAGENTS MARKET BY REGION, 2020 VS 2027 (%)

10. GLOBAL EQUIPMENT MARKET BY REGION, 2020 VS 2027 (%)

11. GLOBAL CUSTOM OLIGOS MARKET BY REGION, 2020 VS 2027 (%)

12. GLOBAL PREDESIGNED OLIGOS MARKET BY REGION, 2020 VS 2027 (%)

13. GLOBAL HOSPITALS MARKET BY REGION, 2020 VS 2027 (%)

14. GLOBAL PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES MARKET BY REGION, 2020 VS 2027 (%)

15. GLOBAL ACADEMIC RESEARCH INSTITUTES MARKET BY REGION, 2020 VS 2027 (%)

16. GLOBAL OTHER OLIGONUCLEOTIDE SYNTHESIS MARKET BY REGION, 2020 VS 2027 (%)

17. US OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

18. CANADA OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

19. UK OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

20. FRANCE OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

21. GERMANY OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

22. ITALY OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

23. SPAIN OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

24. REST OF EUROPE OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

25. INDIA OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

26. CHINA OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

27. JAPAN OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

28. SOUTH KOREA OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

29. REST OF ASIA-PACIFIC OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)

30. REST OF THE WORLD OLIGONUCLEOTIDE SYNTHESIS MARKET SIZE, 2020-2027 ($ MILLION)