A Comprehensive Analysis of the Global Oral and Dental Probiotics Market

Published: Aug 2023

In the ever-evolving healthcare and wellness landscape, the global oral and dental probiotics market has emerged as a promising sector with immense potential for growth. As oral health gains prominence in the overall well-being of individuals, the demand for innovative solutions has led to the rapid expansion of this market. This article includes an understanding of Oral and Dental Probiotics, market size and growth factors, key market players, and recent trends and developments in the Oral and Dental Probiotics market.

Understanding Oral and Dental Probiotics

Oral and dental probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host by promoting a balanced oral microbiome. These friendly bacteria work harmoniously with the body to maintain oral health, prevent cavities, gum diseases, and even combat bad breath. Their ability to restore and maintain a natural balance of beneficial bacteria in the mouth is at the core of their effectiveness.

Market Size and Growth

The global oral and dental probiotics market has grown remarkably in recent years. As per the market research report by OMR, the market is significantly increasing by a CAGR of 8.5% during the forecast period (2023-30). Several factors contribute to this growth:

Increasing Awareness 

Growing awareness about the importance of oral health and hygiene, coupled with a preference for natural and preventive approaches, has led consumers to explore oral and dental probiotics.

Rising Dental Disorders

The prevalence of dental disorders, including cavities and gum diseases, has surged, driving individuals to seek alternative solutions to traditional dental care. According to WHO, Untreated dental caries is the single most common condition globally, affecting an estimated 2.5 billion people.

Technological Advancements

Ongoing research and technological advancements have led to the development of innovative probiotic formulations, making them more effective and accessible. For instance, in June 2021, Probiotic player Probi completed the first commercial production batches of a dairy-free BLIS K12 at its US manufacturing site, with the new BLIS strains available shortly to global customers.

Key Market Players

Several companies are at the forefront of the global oral and dental probiotics market. These include:Lallamand Inc., Chr. Hansen Holding A/S, NOW Health Group, Inc., Oragenics, Inc., and ProBiora Health, LLC.

ProBiotix Health

Renowned for its research-backed probiotic products, ProBiotix Health has developed a range of oral probiotics targeting specific oral health concerns. The company is consistently growing and expanding its business. For instance- 

• ProBiotix Health signed an exclusive distribution agreement with Trans Chem to cover the Australian and New Zealand probiotics market.

ProBiora Health

ProBiora Health is a leading manufacturer and supplier of oral probiotics products. The company develops and markets probiotic solutions for maintaining oral health and promoting fresh breath. Their flagship product, ProBioraPro, is clinically tested and backed by years of scientific research.

• ProBiora Health™, LLC, is rebranding its complete line of probiotics for oral health in people and pets under the ProBiora brand. EvoraPro®, EvoraPlus®, EvoraXtra™, and EvoraPet® and will now be known as ProBiora™Pro, ProBiora™Plus, ProBiora™Xtra, and ProBiora™Pet. The rebranding is part of ProBiora Health’s initiative to align the company’s brand towards its mission of applying the science of probiotics to support oral health.

Probi AB

Probi® is a global company focused exclusively on researching, manufacturing, and delivering probiotics for supplements and functional food.

• In May 2023, Probi took over all BLIS K12 and BLIS M18 distribution in the US and Canada and partnered with the Blis Technologies distribution agreement.

• Symrise-Probi partnership yielded processed probiotics for oral health and launched its first processed probiotic dedicated to oral health. SymReboot OC has proven efficacy in strengthening gums and promoting a healthy oral microbiome. It can be used in various products, including toothpaste, mouthwash, lozenges, and gum care.

Recent Developments

The global oral and dental probiotics market has witnessed significant developments in recent times:

FDA Approvals

The U.S. Food and Drug Administration (FDA) has approved several oral and dental probiotic products, boosting market growth and consumer confidence.

• In April 2023, OraTicx's flagship oral probiotic strain, oraCMU, received FDA GRAS approval. This significant milestone acknowledges the safety and technical capabilities of oraCMU, a strain that has demonstrated promising results in inhibiting dental caries and periodontitis-causing bacteria.

Research Advancements

Ongoing research into the specific strains of bacteria that benefit oral health has created more targeted and effective probiotic formulations.

• In November 2020, Chr. Hansen introduced probiotic lozenges with scientifically documented ingredients that dissolve in the mouth and aid in maintaining dental health. The product comes with a unique combination of the world’s most documented probiotic strain LGG and the L. CASEI 431 probiotic strain.

New Product Developments, Partnerships, and Collaborations

Oral probiotic companies have been entering strategic partnerships and collaborations to expand their product portfolios and market reach.

• In June 2023, Mouthgenics launched its flagship product- Dental Probiotics, which is available in the market for purchase from July 2023. The chewable tablet is formulated with a powerful blend of probiotics and ingredients, scientifically proven to neutralize unpleasant odors and promote fresher breath. Unlike mouthwashes or sprays that offer temporary relief and do more harm than good, Mouthgenics' unique formula tackles bad breath from the root cause, showing long-lasting results and promoting sustained oral freshness.

• In April 2022, ProBioraKids®, the First Probiotic Specially Formulated to Support Kids' Oral and Overall Health, Launches in the US.

• In December 2021, the newly launched start-up business Mintly launched a range of eco-friendly oral wellness products that include new-format toothpaste tablets, mint lozenges with probiotics, and eco options for toothbrushes and floss to promote mouth health.

• In August 2021, Symrise launched SymReboot™ OC, it's first processed probiotic dedicated to oral care. SymReboot™ OC is a COSMOS-approved soothing ingredient with proven efficacy in strengthening gums and promoting a healthy oral microbiome.

The global oral and dental probiotics market is on an upward trajectory, fueled by increasing awareness of oral health and the demand for natural preventive solutions. With significant research and development investments, regulatory approvals, and consumer trust, the market is poised for continued growth in the coming years. As the world recognizes the pivotal role of oral health in overall well-being, oral and dental probiotics are set to play an increasingly essential role in healthcare and wellness. However, the market still needs to be explored in many regions and requires enormous scope for custom research and development.