The global Clozapine N Oxide (CNO) market is expected to grow at a significant CAGR during the forecast period. Clozapine-N-oxide is long been the ligand of choice for selectively activating designer receptors exclusively activated by designer drugs (DREADDs). DREADDs are a group of designed human muscarinic receptors that react only to the synthetic ligand clozapine N-Oxide. They have become a popular tool among neuroscience researchers. 

This tool includes synthetic G-protein-coupled receptors that are triggered by the ordinarily inert CNO and are not expected to be activated by an endogenous ligand. However, it has recently been demonstrated that CNO administration results in measurable quantities of the bioactive compounds clozapine and N-desmethylclozapine in humans and rats. Clozapine is the first atypical antipsychotic and psychiatric medicine. It is used to treat schizophrenia and schizoaffective disorders, as well as other mood and mental disorders. 

Clozapine is often prescribed as a tablet or a liquid for patients with schizophrenia who have had a negative reaction to other antipsychotics or who are unable to take other medications due to extrapyramidal side effects. It's also used to treat psychosis in people with Parkinson's disease. Clozapine is the first atypical antipsychotic and psychiatric medicine. It is used to treat schizophrenia and schizoaffective disorders, as well as other mood and mental disorders. This is listed on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. The increasing prevalence of mental health issues and neurological disorders among people is leading to an increasing demand for clozapine N-oxide across the globe. 

Market Coverage

• The market number available for – 2020-2027
• Base year- 2020
• Forecast period- 2021-2027
• Segment covered 

o By Type

o By Application

• Region covered

o North America

o Europe

o Asia-pacific

o Rest of world

• Competitive Landscape- R&D Systems, Abcam plc, Cayman Chemical, among others. 

Key questions addressed by the report

• What is the market growth rate?
• Which segment and region dominates the market in base year?
• Which segment and region will project fastest growth in the market?
• How COVID-19 impacted the market?

o Recovery Timeline

o Deviation from pre-COVID forecast

o Most affected region and segment

• Who is the leader in the market?
• How players are addressing challenges to sustain growth?
• Where is the investment opportunity?

Global Clozapine N Oxide Market Segmentation 

• By Type

o Low Purity (Below 97%)

o Purity (Above 97% and Below 99%)

o High Purity (Above 99%)

• By Application 

o Cancer Treatment

o Neurological Treatment

o Endocrinological Treatment

o Others

Global Clozapine N Oxide Market by Region