The global glucosylceramidase market is anticipated to grow at a significant CAGR 2.9% during the forecast period (2022-2028). Glucosylceramidase belongs to the genus of hydrolases that catalyze the hydrolysis of glucocerebroside resulting in to glucose and ceramide, that is a normal decomposition pathway for membrane lipids. If Beta-glucocerebrosidase enzyme activity is compromised, this leads to the accumulation of lipid glucocerebroside in tissue macrophages (Gaucher cells). However, while combined with enzyme replacement therapy, there are less chances for glucocerebroside to gather in the body which results in the elevation of serum levels of the enzyme. Clinically, glucosylceramidase finds application in the treatment of various diseases such as genetic disorders, Gaucher disease, and Parkinson's disease, among others. Owing to the deficiency in Beta-glucocerebrosidase enzymatic activity, there is an occurrence of the accumulation of lipid glucocerebroside in tissue macrophages (Gaucher cells) which results in Gaucher disease. 

Among all these disorders, the major factor that propels the market growth include the significant prevalence of Parkinson’s diseases across the globe. According to Parkinson’s Foundation in 2019, more than 10 million people across the globe were living with Parkinson’s disease. There is no specific treatment available for Parkinson's disease; however, various clinical trials are in their pipeline phase, among which glucosylceramidase is likely to show promising results. This is likely to support the growth of the global glucosylceramidase market. 

Market Coverage

• The market number available for – 2021-2028

• Base year- 2021

• Forecast period- 2022-2028

• Segment Covered- 

o By Type

o By Application

• Regions covered-

o North America

o Europe

o Asia-Pacific

o Rest of the World

• Competitive Landscape:  Avrobio, Inc., and Amicus Therapeutics, Inc., among others.

Key questions addressed by the report

• What is the market growth rate?

• Which segment and region dominate the market in the base year?

• Which segment and region will project the fastest growth in the market?

• How COVID-19 impacted the market?

o Deviation from the pre-COVID-19 forecast

o Most affected region and segment

• Who is the leader in the market?

• How are players addressing challenges to sustain growth?

• Where is the investment opportunity?

Global Glucosylceramidase Market Report by Segment

By Type

• AVRRD-02

• LTI-291.

• NCGC-607

• Others

By Application

• Genetic Disorders

• Gaucher Disease

• Parkinson’s Disease

• Others

Global Glucosylceramidase Market Report by Region

North America       

• US

• Canada

Europe

• Germany

• UK

• France

• Spain

• Italy

• Rest of Europe

Asia-Pacific    

• China

• Japan

• India

• Rest of Asia-Pacific

Rest of the World

• Latin America

• Middle East and Africa